Tag Archives: haemoglobin s

Casgevy and Lyfgenia: Gene Therapy Innovations in the Treatment of Sickle Cell Disease

Abstract Sickle Cell Disease (SCD) is a severe hereditary blood disorder that affects millions worldwide, primarily individuals of African, Mediterranean, Middle Eastern, and Indian descent. The disease is characterised by the presence of abnormal haemoglobin S, leading to sickling of red blood cells (RBCs), vaso-occlusive crises (VOCs), and organ damage. Historically, treatment options have been […]

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