Abstract Pain in Sickle Cell Disease (SCD) is one of the most debilitating symptoms, often leading to acute and chronic suffering. This paper explores the neurophysiological pathways involved in the initiation and transmission of pain in SCD, highlighting the root causes, such as nerve fibres, pain sensors, and their interactions. The paper further investigates the […]
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The Role of Nitrate and Nitrite in Regulating Atomic and Molecular Spin for Cellular Balance and the Management of Sickle Cell Disease
Abstract The regulation of atomic and molecular spin at the cellular level plays a fundamental role in maintaining biological harmony. In the context of sickle cell disease (SCD), abnormal haemoglobin polymerisation leads to the characteristic sickling of red blood cells, impairing oxygen delivery and causing systemic complications. This paper explores how nitrate (NO₃⁻) and nitrite […]